CURRICULUM VITAE

Education:

May 1974 - B. S.Chemistry, University of North Carolina at Chapel Hill Chapel Hill, North Carolina (Advisor:  Dr. John H. Harrison)
June 1977 - Student Physiology Course, Marine Biology Laboratory, Woods Hole, Massachusetts
Feb. 1980 - Ph.D. Biology, Brandeis University, Waltham, Massachusetts  (Advisor:  Dr. Andrew G. Szent-Gyorgyi). Thesis:  Role of the Light Chain in the Regulation of Myosin

The Biophysical Society
The American Society for Cell Biology

 
1985-1987    Physiol. Chem. Research Study Group, American Heart Association (AHA)
1987-1988    Chairman of Contractility Subgroup, Biophysical Society
1988-1989    Vice President, NHLBI Assembly of Scientists
1990-1992    Molecular Biology of Muscle Research Study Group, AHA
1994-1997    Co-chair, Molecular Biology of Muscle Research Study Group, AHA
1991-1997    Ad Hoc Member of Physiology Study Section, NIH
1993             Chairman of Gordon Conference on Muscle Protein and Contractility
1997             Co-organizer of "A Myosin Family Reunion", an international meeting held in honor of the 50th Anniversary of the NHLBI
1999-2002    Molecular Genetics Research Study Group, AHA

1988-1992   Editorial Board, Journal of Biological Chemistry
1992-1997   Editorial Board, Journal of Muscle Research and Cell Motility
1996-2000   Managing Editor, Journal of Muscle Research and Cell Motility

1974-1975    Bernard and Mirriam Kessner Fellowship, Brandeis University
1975-1977    N.I.H. Developmental Biology Training Grant
1979-1981    Muscular Dystrophy Association of America. Post-doctoral fellow, at the National Institutes of Health, Bethesda, Maryland
1981-1984    Staff Fellow, Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland
1983-1984    Acting Chief, Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland
1984-1985    Senior Staff Fellow, Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland
1985-1991    Senior Investigator, Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland
1991-Present    Chief, Section on Cellular and Molecular Motility, Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland

1. Lang, F., Ogonowski, M.M., Costello, W.J., Hill, R., Roehrig, B., Kent, K. and Sellers, J.R.:  Neurotrophic influence on lobster skeletal muscle.  Science 207:  325-327, 1980.

 
2. Sellers, J.R., Chantler, P.D. and Szent-Gyorgyi, A.G.: Hybrid formation between scallop myofibril and foreign regulatory light chains.  J. Mol. Biol. 144:  223-245, 1980.

 
3. Adelstein, R.S., Pato, M.D., Sellers, J.R., Conti, M.A. and Eaton, C.R.:  Regulation of contraction by reversible phosphorylation of myosin and myosin kinase.  Cold Spring Harbor Conference on Cell Proliferation. Vol 8, 811-822, 1980.

 
4. Chantler, P.D., Sellers, J.R. and Szent-Gyorgyi, A.G.:  Cooperativity in scallop myosin.  Biochemistry 20:  210-216, 1981.

 
5. Sellers, J.R.:  Phosphorylation-dependent regulation of Limulus myosin.  J. Biol. Chem. 256:  9274-9278, 1981.

 
6. Sellers, J.R., Pato, M.D. and Adelstein, R.S.:  Reversible phosphorylation of smooth muscle myosin, heavy meromyosin and platelet myosin.  J. Biol. Chem. 256:  13137 13142, 1981.

 
7. Adelstein, R.S., Pato, M.D., Sellers, J.R., de Lanerolle, P. and Conti, M.A.:  The regulation of contractile proteins by reversible phosphorylation of myosin and myosin kinase.  in Twarog, B.M., Levine, R.J.C. and Dewey, M.M. (Eds.): Basic Biology of Muscles.  A Comparative Approach.  New York, Raven Press, pp. 273-281, 1981.

 
8. Sellers, J.R., Eisenberg, E. and Adelstein, R.S.:  The binding of smooth muscle heavy meromyosin to actin in the presence of ATP.  Effect of phosphorylation.  J. Biol. Chem. 257:  13880-13883, 1982.

 
9. Adelstein, R.S., Pato, M.D., Sellers, J.R., de Landerolle, P. and Conti, M.A.:  Regulation of actin-myosin interaction by reversible phosphorylation of myosin kinase.  in Harbor Conference Symposium on Quantitative Biology XLVI: 921-928, 1982.

 
10. Adelstein, R.S., de Lanerolle, P., Sellers, J.R., Pato, M.D. and Conti, M.A.:  Regulation of contractile proteins in smooth muscle and platelets by calmodulin and cyclic AMP.  in Recent Advances in Ca2+ and Cell Function. Calmodulin and Intracellular Ca2+-Receptor. Kyoto, Japan, pp. 313-331, 1982.

 
11. Adelstein, R.S., Sellers, J.R., Conti, M.A., Pato, M.D. and de Lanerolle, P.:  Regulation of smooth muscle proteins by calmodulin and cyclic AMP.  Fed. Proc. 41:  2873-2878, 1982.

 
12. Greene, L.E., Sellers, J.R., Eisenberg, E. and Adelstein, R.S.:  Binding of gizzard smooth muscle subfragment-one to actin in the presence and absence of ATP.  Biochemistry 22:  530-535, 1983.

 
13. Sellers, J.R., Chock, P.B. and Adelstein, R.S.:  The apparently negatively cooperative phosphorylation of smooth muscle myosin at low ionic strength is related to its filamentous state.  J. Biol. Chem. 258:  14181-14188, 1983.

 
14. Pato, M.D., Sellers, J.R., Conti, M.A. and Adelstein, R.S.:  Reversible phosphorylation of smooth muscle myosin and myosin kinase.  in Stephens, Newman, L. (Ed.):  Smooth Muscle Contraction.  New York and Basel, Marcel Dekker, Inc., 1984.

 
15. Hammer, J.H., Sellers, J.R. and Korn, E.D.:  Phosphorylation and activation of smooth muscle myosin by Acanthamoeba myosin I heavy chain kinase. J. Biol. Chem. 259:  3224-3229, 1984.

 
16. Sellers, J.R. and Pato, M.D.:  The binding of smooth muscle myosin light chain kinase and phosphatases to actin and myosin. J. Biol. Chem.259:  7740-7746, 1984.

 
17. Sussman, D.J., Sellers, J.R., Flicker, P.F., Lai, E.Y., Cannon, L.E., Szent-Gyorgyi, A.G. and Fulton, C.:  Actin of Naegleria Gruberi.  J. Biol. Chem. 259:  7349-7354, 1984.

 
18. Nishikawa, M., Sellers, J.R., Adelstein, R.S. and Hidaka, H.:  Protein kinase C modulates in vitro phosphorylation of smooth muscle heavy meromyosin by myosin light chain kinase.  J. Biol. Chem. 259:  8808-8814, 1984.

 
19. Sellers, J.R. and Harvey, E.V.:  Purification of Limulus myosin light chain kinase.  Biochemistry 23:  5821-5826, 1984.

 
20. Sellers, J.R. and Harvey, E.V.:  Localization of a light chain binding site on smooth muscle myosin revealed by a light chain overlay of SDS-polyacrylamide electrophoretic gels.  J. Biol. Chem. 259:  14203-14207, 1984.

 
21. Margossian, S.S., Chantler, P.D., Sellers, J.R., Malhotra, A., Stafford, W.F. and Slayter, H.S.:  Proteolytic susceptibility of both isolated and bound light chains from various myosins to myopthatic hamster protease. J. Biol. Chem. 259:  13534-13540, 1984.

 
22. Schneider, M.D., Sellers, J.R., Vahey, M., Preston, Y.A. and Adelstein, R.S.:  Localization and topography of antigenic domains within the heavy chain of smooth muscle myosin.  J. Cell Biol. 101:  66-72, 1985.

 
23. Sellers, J.R. and Adelstein, R.S.:  The mechanism of regulation of smooth muscle myosin by phosphorylation.  Current Topics in Cellular Regulation. Vol. 27, 51-62, 1985.

 
24. Adelstein, R.S., de Lanerolle, P., Nishikawa, M. and Sellers, J.R.:  The regulation of smooth muscle contraction by phosphorylation.  in Bevan, J.A. et al. (Eds.):  Vascular Neuroeffector Mechanisms.  Amsterdam, New York, Oxford, Elsevier Science Publishers, pp. 63-67, 1985.

 
25. Sellers, J.R.:  Mechanism of the phosphorylation-dependent regulation of smooth muscle heavy meromyosin.  J. Biol. Chem. 260:  15815-15819, 1985.

 
26. Sellers, J.R., Spudich, J.A. and Sheetz, M.P.:  Light chain phosphorylation regulates the movement of smooth muscle myosin on actin filaments. J. Cell Biol. 101:  1897-1902, 1985.

 
27. Lash, J.A., Sellers, J.R. and Hathaway, D.R.:  The effects of caldesmon on smooth muscle acto-HMM ATPase activity and binding of HMM to actin. J. Biol. Chem. 261:  16155-16160, 1986.

 
28. Adelstein, R.S. and Sellers, J.R.:  The effects of calcium on vascular smooth muscle contraction.  Am. J. Cardiol. 59: 4B-10B, 1987.

 
29. Sellers, J.R. and Adelstein, R.S.:  Regulation of contractile processes by phosphorylation.  The Enzymes Vol. XVIII, Part B, 381-418, 1987.

 
30. Greene, L.E. and Sellers, J.R.:  Effect of phosphorylation on the binding of smooth muscle HMM-ADP to actin.  J. Biol. Chem. 262: 4177-4181, 1987.

 
31. Bengur, A.R., Robinson, E.A., Appella, E. and Sellers, J.R.:  Sequence of the sites phosphorylated by protein kinase C in the smooth muscle myosin light chain.  J. Biol. Chem. 262:  7613-7617, 1987.

 
32. Sellers, J.R., Soboeiro, M.S., Faust, K., Bengur, A.R. and Harvey, E.V.:  Preparation and characterization of heavy meromyosin and subfragment-one from vertebrate cytoplasmic myosins.  Biochemistry 27: 6977-6982, 1988.

 
33. Umemoto, S., Bengur, A.R. and Sellers, J.R.:  Effect of phosphorylation of smooth muscle and cytoplasmic myosins on movement in an in vitro motility assay.  J. Biol. Chem. 264:  1431-1436, 1989.

 
34. Kawamoto, S., Bengur A.R., Sellers, J.R. and Adelstein, R.S.:  Insitu phosphorylation of human platelet myosin heavy and light chains by protein kinase C.  J. Biol. Chem. 264:  2258-2265, 1989.

 
35. Margossian, S.S., Sellers, J.R., Watkins, S.C. and Slayter, H.S.:  Formation of new, quasi-crystalline ordered aggregates by chicken gizzard myosin.  J. Muscle Res. Cell Motil. 10:  413-426, 1989.

 
36. Collins, K., Sellers, J.R. and Matsudaira, P.:  Calmodulin dissociation regulates brush border myosin I (110-kD-calmodulin) mechanochemical activity in vitro.  J. Cell Biol. 110:  1137-1147, 1990.

 
37. Sellers, J.R. and Umemoto, S.:  Effect of multiple phosphorylations on movement of smooth muscle and cytoplasmic myosin.  in Hidaka, H. (Ed.):  Advances in Experimental Medicine and Biology (Calcium Protein Signaling).  New York, Plenum Press, Vol. 255, pp. 299-304, 1990.

 
38. Adelstein, R.S., Beaven, M.A., Bengur, A.R., Kawamoto, S., Ludowyke, R.I., Peleg, I. and Sellers, J.R.:  In situ phosphorylation of human platelet and rat basophilic leukemia cell (RBL-2H3) myosin heavy chain and light chain.  in Hidaka, H. (Ed.):  Advances in Experimental Medicine and Biology (Calcium Protein Signaling).  New York, Plenum Press, Vol. 255, pp. 289-297, 1990.

 
39. Corson, M.A., Sellers, J.R., Adelstein, R.S. and Schoenberg, M.:  Substance P contracts bovine tracheal smooth muscle via activation of myosin light chain kinase.  Am. J. Physiol. 259:  C258-C265, 1990.

 
40. Sellers, J.R. and Kachar, B.:  Polarity and velocity of sliding filaments:  Control of direction by actin and of speed by myosin.  Science249:  406-408, 1990.

 
41. Umemoto, S. and Sellers, J.R.:  Characterization of in vitro motility assays using smooth muscle and cytoplasmic myosins.  J. Biol. Chem. 265:  14864-14869, 1990.

 
42. Conti, M.A., Sellers, J.R., Adelstein, R.S. and Elzinga, M.:  Identification of the serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains.  Biochemistry 30:  966-970, 1991.

 
43. Sellers, J.R.:  Regulation of cytoplasmic and smooth muscle myosin. Curr. Opin. Cell Biology 3:  98-104, 1991.

 
44. Margossian, S.S., Krueger, J.W., Sellers, J.R., Cuda, G., Caulfield, J.B., Norton, P. and Slayter, H.S.:  Influence of the cardiac myosin hinge region on contractile activity.  Proc. Natl. Acad. Sci. USA88:  4941-4945, 1991.

 
45. Sellers, J.R., Han, Y.J. and Kachar, B.:  The use of native thick filaments in in vitro motility assays.  J. Cell Sci.14: 67-71, 1991.

 
46. Sobue, K. and Sellers, J.R.:  Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems.  J. Biol. Chem.266:  12115-12118, 1991.

 
47. Hettasch, J.M. and Sellers, J.R.:  Caldesmon phosphorylation in intact human platelets by cAMP-dependent protein kinase and protein kinase C. J. Biol. Chem. 261:  11876-11881, 1991.

 
48. Collins, K., Sellers, J. and Matsudaira, P.:  Myosin I:  A new insight into the mechanism and cellular significance of actin-based motility.  in Kotani, M. (Ed.):  Advances in Biophysics.  Japan Scientific Societies Press, Japan/Elsevier, Ireland, Vol. 27, pp. 221 226, 1991.

 
49. Sellers, J.R. and Homsher, E.:  A giant step for myosin.  Curr. Biol. 1:  347-349, 1991.

 
50. Nakabayashi, H., Sellers, J.R. and Huang, K.-P.:  Catalytic fragment of protein kinase C exhibits altered substrate specificity toward smooth muscle myosin light chain.  FEBS Lett. 294:  144-148, 1991.

 
51. Homsher, E., Wang, F. and Sellers, J.:  Factors affecting the movement of F-actin filaments propelled by skeletal muscle heavy meromyosin. Am. J. Physiol. 262:  C714 C723, 1992.

 
52. Kelley, C.A., Sellers, J.R., Goldsmith, P.K. and Adelstein, R.S.:  Smooth muscle myosin is composed of homodimeric heavy chains.  J. Biol. Chem. 267:  2127-2130, 1992.

 
53. Janson, L.W., Sellers, J.R. and Taylor, D.L.:  Actin-binding proteins regulate the work performed by myosin II motors on single actin filaments. Cell Motil. Cytoskel. 22:  274-280, 1992.

 
54. Shirinsky, V.P., Biryukov, K.G., Hettasch, J.M. and Sellers, J.R.:  Inhibition of the relative movement of actin and myosin by caldesmon and calponin.  J. Biol. Chem. 267:  15886-15892, 1992.

 
55. Daniel, J.L. and Sellers, J.R.:  Purification and characterization of platelet myosin.  Meth. Enzymol. 215:  78-87, 1992.

 
56. Ganguly, C., Baines, I.C., Korn, E.D. and Sellers, J.:  Regulation of the actin-activated ATPase and in vitro motility activities of monomeric and filamentous Acanthamoeba myosin II.  J. Biol. Chem. 267:  20900-20904, 1992.

 
57. Wang, F., Martin, B.M. and Sellers, J.R.:  Regulation of actomyosin interactions in Limulus muscle proteins.  J. Biol. Chem.268:  3776-3780, 1993.

 
58. Cuda, G., Fananapazir, L., Zhu, W.-S., Sellers, J.R. and Epstein, N.D.:  Skeletal muscle expression and abnormal function of ß-myosin in hypertrophic cardiomyopathy.  J. Clin. Invest. 91:  2861-2865, 1993.

 
59. Sellers, J.R., Umemoto, S. and Cuda, G.:  In vitro studies of determinants of smooth muscle mechanics.  Adv. Exp. Med. Biol.332:  267-276, 1993.

 
60. Homsher, E., Wang, F. and Sellers, J.R.:  Factors affecting filament velocity in in vitro motility assays and their relation to unloaded shortening velocity in muscle fibers.  Adv. Exp. Med. Biol.332:  279-289, 1993.
61. Sellers, J.R., Cuda, G., Wang, F. and Homsher, E.:  Myosin-specific adaptations of the motility assay.  Meth. Cell Biol. 39:  23-49, 1993.

 
62. Shirinsky, V.P., Vorotnikov, A.V., Birukov, K.G., Nanaev, A.K., Collinge, M., Lukas, T.J., Sellers, J.R. and Watterson, D.M.:  A kinase related protein stabilizes unphosphorylated smooth muscle myosin minifilaments in the presence of ATP.  J. Biol. Chem. 268:  16578-16583, 1993.

 
63. Novy, R.E., Sellers, J.R., Liu, L.-F. and Lin, J.J.-C.:  In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants.  Cell Motil. Cytoskel.26:  248-261, 1993.

 
64. Cremo, C.R., Sellers, J.R. and Facemyer, K.C.:  Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin. J. Biol. Chem. 270:  2171-2175, 1995.

 
65. Rayment, I., Holden, H.M., Sellers, J.R., Fananapazir, L. and Epstein, N.D.:  Structural interpretation of the mutations in the ß-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy. Proc. Natl. Acad. Sci. USA 92:  3864-3868, 1995.

 
66. Sellers, J.R. and Goodson, H.V.:  Myosin.  Protein Profile2:  1323-1423, 1995.

 
67. Sellers, J.R.:  In vitro motility assays with smooth muscle myosin.  in Barany, M. (Ed.):  Biochemistry of Smooth Muscle Contraction.  New York, Academic Press, pp. 181-190, 1995.

 
68. Adelstein, R.S. and Sellers, J.R.:  Myosin structure and function.  in Barany, M. (Ed.):  Biochemistry of Smooth Muscle Contraction.  New York, Academic Press, pp. 3-19, 1995.

 
69. Facemyer, K.C., Sellers, J.R. and Cremo, C.R.:  Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin. Biophys. J. 68 Suppl. 228S, 1995.

 
70. Pato, M.D., Sellers, J.R., Preston, Y.A., Harvey, E.V. and Adelstein, R.S.:  Baculovirus expression of chicken nonmuscle heavy meromyosin II-B:  Characterization of alternatively spliced isoforms.  J. Biol. Chem.271:  2689-2695, 1996.

 
71. Sellers, J.R., Goodson, H.V. and Wang, F.:  A myosin family reunion. J. Muscle Res. Cell Motil. 17:  7-22, 1996.

 
72. Poetter, K., Jiang, H., Hassanzadeh, S., Master, S.R., Chang, A., Dalakas, M.C., Rayment, I., Sellers, J.R., Fananapazir, L. and Epstein, N.D.:  Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle. Nature Genet. 13:  63-69, 1996.

 
73. Sellers, J.R.:  NCD and kinesin:  Two structural cousins of myosin. J. Muscle Res. Cell Motil. 17:  173-176, 1996.

 
74. Olney, J., Sellers, J.R. and Cremo, C.R.:  Structure and function of the 10S conformation of smooth muscle myosin.  J. Biol. Chem.271:  20375-20384, 1996.

 
75. Kelley, C.A., Sellers, J.R., Gard, D.L., Bui, D., Adelstein, R.S. and Baines, I.C.: Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.  J. Cell Biol. 134:  675-687, 1996.

 
76. Gerthoffer, W.T., Yamboliev, I.A. Shearer, M., Pohl, J., Haynes, R., Dang, S., Sato, K. and Sellers, J.R.:  J. Physiol. (Lond.) 495:  597-609, 1996.

 
77. Cuda, G., Fananapazir, L., Epstein, N.D. and Sellers, J.R.:  The in vitro motility activity of ß-cardiac myosin depends on the nature of the ß-myosin heavy chain gene mutation in hypertrophic cardiomyopathy. J. Muscle Res. Cell Motil. 18:  275-283, 1997.

 
78. Cuda, G., Pate, E., Cooke, R. and Sellers, J.R.:  In vitro actin filament sliding velocities produced by mixtures of different types of myosin.  Biophys. J. 72:  1767-1779, 1997.

 
79. Wang, Z.-Y., Sakai, J., Matsudaira, P.T., Baines, I.C., Sellers, J.R., Hammer, J.A. III, Korn, E.D.:  The amino acid sequence of the light chain of Acanthamoeba myosin IC.  J. Muscle Res. Cell Motil. 18:  395-398, 1997.

 
80. Pohl, J., Winder, S.J., Walsh, M.P., Sellers, J.R. and Gerthoffer, W.T.:  Phosphorylation of calponin in airway smooth muscle.  J. Physiol. (London) 272:  113-123, 1997.

 
81. Silver, D.L., Vorotnikov, A.V., Watterson, D.M., Shirinsky, V.P., and Sellers, J.R.:  Sites of interaction between kinase-related protein and smooth muscle myosin.  J. Biol.Chem. 272:  25353-25359, 1997.

 
82. Ford, H.L., Silver, D.L., Kachar, B., Sellers, J.R. and Zain, S.B.:  Effect of Mts1 on the structure and activity of nonmuscle myosin II. Biochemistry 36:  16321-16327, 1997.

 
83. Shah, A.M., Mebazaa, A., Yang, Z.K., Cuda, G., Lankford, E.B., Pepper, C.B., Sollott, S.J., Sellers, J.R., Robotham, J.L. and Lakkatta, E.G.:  Inhibition of myocardial crossbridge cycling by hypoxic endothelial cells:  a potential mechanism for matching oxygen supply and demand?  Cir. Res. 80:  688-698, 1997.

 
84. Bonafe, N. and Sellers, J.R.:  Molecular characterization of myosin V from D. melanogaster.  J. Muscle Res. Cell Motil. 19:  129-141, 1998.

 
85. Battelle, B.A., Andrews, A.W., Calman, B.G., Sellers, J.R., Greenberg, R.M.and Smith, W.C.:  A myosin III from Limulus eyes is a clock-regulated phosphoprotein.  J. Neurosci. 18:  4548-4559, 1998.

 
86. Han, Y.J. and Sellers, J.R.:  Motility assays on molluscan native thick filaments.  Methods Enzymol. 298:  427-435, 1998.

 
87. Sweeney, H.L., Rosenfeld, S.S., Brown, F., Faust, L., Smith, J., Xing, J., Stein, L.A. and Sellers, J.R.:  Kinetic tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket.  J. Biol. Chem. 273:  6262-6270, 1998.

 
88. Sellers, J.R. and Jiang, H.:  In vitro motility assays with actin.  in Cell Biology:  A Laboratory Handbook, 2nd Ed., J.Celis, Editor.  Academic Press, San Diego.  Vol. 2, 336-343, 1998.

 
89. Jenkins, A.L., Nannizzi-Alaimo, L., Silver, D., Sellers, J.R., Ginsberg, M.H., Law, D.A. and Phillips, D.R.:  Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates integrin-cytoskeletal interactions.  J. Biol. Chem. 273: 13878-13885, 1998.

 
90. Bonafe, N.M. and Sellers, J.R.:  Calmodulin-binding proteins of the cytoskeleton.  in Calmodulin and Signal Tranduction, L. Van Eldik and D.M. Watterson, Editors.  Academic Press, San Diego, 347-395, 1998.

 
91. Wang, Z.-Y., Wang, F., Sellers, J.R., Korn, E.D. and Hammer, J.A. III:  Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis.  Proc. Natl. Acad. Sci. USA 95:  15200-15205, 1998.

 
92. Sellers, J.R.:  Protein Profile:  Myosins.  2^nd Ed., Oxford University Press, Oxford, 1999.

 
93. Sellers, J.R.:  Unphosphorylated crossbridges and latch:  smooth muscle regulation revisited.  J. Muscle Res. Cell Motil. 20:  347-349, 1999.

 
94. Liang, Y., Wang, A., Belyantseva, I.A., Anderson, D.W., Probst, F.J., Barber, T.D., Miller, W., Touchman, J.W., Jin, L., Sullivan, S.L., Sellers, J.R., Camper, S.A., Lloyd, R.V., Bachar, B., Friedman, T.B. and Fridell, R.A.:  Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and Shaker 2.  Genomics 61:  243-258, 1999.

 
95. Friedman, T.B., Sellers, J.R. and Avraham, K.B.:  Unconventional myosins and the genetics of hearing loss.  Am. J. Human Genet. 89:  147-157, 1999

 
96. Kudryashov, D.S., Chibalina, M.V., Birukov, K.G., Lukas, T.J., Sellers, J.R., Van Eldik, L.J., Watterson, D.M. and Shirinsky, V.P.:  Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton.  FEBS Lett. 463:  67-71, 1999.

 
97. Wang, F., Chen, L., Arcucci, O., Harvey, E.V., Bowers, B., Xu, Y., Hammer, J.A. III and Sellers, J.R.:  Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V.  J. Biol. Chem. 275: 4329-4335, 2000.

 
98. Sellers, J.R.:  Myosins:  a diverse superfamily.  Biochim. Biophys. Acta. 1496:  3-22, 2000.

 
99. Wang, F., Harvey, E.V., Conti, M.A., Wei, D. and Sellers, J.R.:  A conserved negatively charged amino acid modulates function in human nonmuscle myosin IIA.  Biochemistry 39:  5555-5560, 2000.

 
100. Ellison, P.A., Sellers, J.R. and Cremo, C.R.:  Kinetic properties of smooth muscle heavy meromyosin with one-head thiophosphorylated. J. Biol. Chem. 275:  15142-15151, 2000.

 
101. Walker, M.L., Burgess, S.A., Sellers, J.R., Wang, F., Hammer, J.A. III, Trinick, J. and Knight, P.J.:  Two-headed binding of a processive myosin to F-actin.  Nature 405:  804-807, 2000.
102. Yamashita, R.A., Sellers, J.R. and Anderson, J.B.:  Identification and analysis of the myosin superfamily in Drosophila:  A database approach.  J. Muscle Res. Cell Motil. 21:  491-505, 2000.
103. Cremo, C.R., Wang, F., Facemyer, K. and Sellers, J.R.:  Phosphorylation-dependent regulation is absent in a nonmuscle heavy meromyosin construct with one complete head and one head lacking the motor domain.  J. Biol. Chem. 276:  41465-41472, 2001.
104. Gillespie, P.G., Albanesi, J.P., Bahler, M., Bement, W.M., Berg, J.S., Burgess, D.R., Burnside, B., Cheney, R.E., Corey, D.P., Coudrier, E., de Lanerolle, P., Hammer, J.A., Hasson, T., Holt, J.R., Hudspeth, A.J., Ikebe, M., Kendrick-Jones, J., Korn, E.D., Li, R., Mercer, J.A., Milligan, R.A., Mooseker, M.S., Ostap, E.M., Petit, C., Pollard, T.D., Sellers, J.R., Soldati, T. and Titus, M.A.:  Myosin-I nomenclature.  J. Cell Biol.155:  703-704, 2001.
105. Veigel, C., Wang, F., Bartoo, M.L., Sellers, J.R. and Molloy, J.E.:  The gated gait of the processive molecular motor, myosin V.  Nature Cell Biol. 4:  59-65, 2002.
106. Wu, X.S., Rao, K., Zhang, H., Wang, F., Sellers, J.R., Copeland, N.G., Jenkins, N.A. and Hammer, J.A. III:  Identification of an organelle receptor for myosin Va.  Nature Cell Biol. 4:  271-278, 2002.
107. Boger, E.T., Sellers, J.R. and Friedman, T.B.:  Human myosin XVBP is a transcribed pseudogene.  J. Muscle Res. Cell Motil. 22:  477-483, 2002.
108. Wu, X., Wang, F., Rao, K., Sellers, J.R. and Hammer, J.A. III:  Rab27a is an essential component of the melanosome receptor for myosin Va.  Mol. Biol. Cell 13:  1735-1749, 2002.
109. Hu, A., Wang, F. and Sellers, J.R.:  Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin Anomaly and Fechtner Syndrome result in impaired enzymatic function.  J. Biol. Chem., in revision.
110. Sellers, J.R., Wang, F. and Chantler, P.D.:  Trifluoperazine inhibits the MgATPase activity and in vitro motility of conventional and unconventional myosins.  Biochemistry, submitted.