| Protein Name | Gene Name | Peptide # | Acc No | GO Component | GO Process | GO Function | Tech |
| alpha 1B- glycoprotein | A1BG | 1 | NP_570602 | extracellular region | not classified | not classified | 2 |
| alpha- 2- macroglobulin- like 1 | A2ML1 | 1 | NP_653271 | not classified | not classified | endopeptidase inhibitor activity | 2 |
| aminoadipate- semialdehyde dehydrogenase- phosphopantetheinyl transferase | AASDHPPT | 1 | NP_056238 | not classified | fatty acid biosynthesis | magnesium ion binding
phosphopantetheinyltransferase activity
transferase activity | 2 |
| ATP- binding cassette sub- family B member 1 | ABCB1 | 23 | NP_000918 | cell surface
integral to membrane
membrane
membrane fraction | response to drug
transport | ATP binding
ATPase activity
hydrolase activity
nucleotide binding
transporter activity
xenobiotic- transporting ATPase activity | 1, 2 |
| ATP- binding cassette, sub- family B (MDR/TAP), member 11 | ABCB11 | 1 | NP_003733 | integral to plasma membrane
membrane
membrane fraction | transport | ATP binding
ATPase activity
bile acid- exporting ATPase activity
nucleotide binding
sodium- exporting ATPase activity, phosphorylative mechanism
transporter activity | 2 |
| ATP- binding cassette, sub- family B, member 6 | ABCB6 | 1 | NP_005680 | ATP- binding cassette (ABC) transporter complex
integral to membrane
membrane
mitochondrial envelope
mitochondrion | iron ion homeostasis
transport | ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
nucleotide binding | 2 |
| ATP- binding cassette, sub- family C, member 11 isoform a | ABCC11 | 1 | NP_149163 | integral to membrane
membrane | transport | ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
nucleotide binding | 2 |
| ATP- binding cassette, sub- family C, member 9 isoform SUR2A- delta- 14 | ABCC9 | 1 | NP_064694 | integral to membrane
membrane | potassium ion transport
transport | ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
nucleotide binding
receptor activity
sulfonylurea receptor activity
transporter activity | 2 |
| abhydrolase domain containing 14B | ABHD14B | 6 | NP_116139 | nucleus | not classified | not classified | 1, 2 |
| abl- interactor 1 isoform d | ABI1 | 2 | NP_001012770 | cytoskeleton
cytosol
endoplasmic reticulum
nucleus
soluble fraction | negative regulation of cell proliferation
transmembrane receptor protein tyrosine
kinase signaling pathway | cytoskeletal protein binding | 2 |
| acetyl- Coenzyme A acetyltransferase 1 precursor | ACAT1 | 1 | NP_000010 | mitochondrion | not classified | acetyl- CoA C- acetyltransferase activity
acyltransferase activity
transferase activity | 2 |
| angiotensin I converting enzyme isoform 1 precursor | ACE | 23 | NP_000780 | integral to membrane
membrane
membrane fraction
plasma membrane
soluble fraction | blood pressure regulation
metabolism
proteolysis | carboxypeptidase activity
chloride ion binding
hydrolase activity, acting on glycosyl bonds
metal ion binding
peptidyl- dipeptidase A activity
zinc ion binding | 1, 2 |
| angiotensin I converting enzyme isoform 2 precursor | ACE | 12 | NP_690043 | integral to membrane
membrane
membrane fraction
plasma membrane
soluble fraction | blood pressure regulation
metabolism
proteolysis | carboxypeptidase activity
chloride ion binding
hydrolase activity, acting on glycosyl bonds
metal ion binding
peptidyl- dipeptidase A activity
zinc ion binding | 2 |
| angiotensin I converting enzyme 2 precursor | ACE2 | 8 | NP_068576 | extracellular region
integral to membrane
membrane | entry of virus into host cell
proteolysis | carboxypeptidase activity
chloride ion binding
metal ion binding
peptidyl- dipeptidase A activity
protein binding
viral receptor activity
zinc ion binding | 2 |
| ATP citrate lyase isoform 2 | ACLY | 1 | NP_942127 | citrate lyase complex | ATP catabolism
citrate metabolism
coenzyme A metabolism
lipid biosynthesis
metabolism | ATP binding
ATP citrate synthase activity
catalytic activity
magnesium ion binding
nucleotide binding
transferase activity | 2 |
| ATP citrate lyase isoform 1 | ACLY | 1 | NP_001087 | citrate lyase complex | ATP catabolism
citrate metabolism
coenzyme A metabolism
lipid biosynthesis
metabolism | ATP binding
ATP citrate synthase activity
catalytic activity
magnesium ion binding
nucleotide binding
transferase activity | 1 |
| aconitase 1 | ACO1 | 6 | NP_002188 | cytoplasm | metabolism
tricarboxylic acid cycle | 4 iron, 4 sulfur cluster binding
aconitate hydratase activity
iron ion binding
lyase activity
metal ion binding
RNA binding | 2 |
| thioesterase, adipose associated isoform BFIT2 | ACOT11 | 1 | NP_671517 | cytoplasm | fatty acid metabolism
intracellular signaling cascade
response to temperature stimulus | acyl- CoA thioesterase activity
hydrolase activity
serine esterase activity | 2 |
| acyl- CoA thioesterase 7 isoform hBACHd | ACOT7 | 1 | NP_863656 | cytoplasm
mitochondrion | lipid metabolism | acyl- CoA binding
hydrolase activity
palmitoyl- CoA hydrolase activity
serine esterase activity | 2 |
| acid phosphatase 1 isoform b | ACP1 | 1 | NP_009030 | cytoplasm
soluble fraction | protein amino acid
dephosphorylation | acid phosphatase activity
hydrolase activity
non- membrane spanning protein tyrosine phosphatase activity
protein tyrosine phosphatase activity | 2 |
| lysosomal acid phosphatase 2 precursor | ACP2 | 7 | NP_001601 | integral to membrane
lysosomal membrane
lysosome | not classified | acid phosphatase activity
hydrolase activity | 1, 2 |
| prostatic acid phosphatase precursor | ACPP | 8 | NP_001090 | extracellular region | regulation of progression
through cell cycle | acid phosphatase activity
hydrolase activity
protein tyrosine phosphatase activity | 1, 2 |
| acyl- CoA synthetase long- chain family member 4 isoform 2 | ACSL4 | 1 | NP_075266 | integral to membrane
membrane
peroxisome | fatty acid metabolism
learning and/or memory
lipid metabolism
metabolism | ligase activity
long- chain- fatty- acid- CoA ligase activity
magnesium ion binding | 2 |
| acyl- CoA synthetase medium- chain family member 1 | ACSM1 | 1 | NP_443188 | mitochondrial matrix | benzoate metabolism
butyrate metabolism
energy derivation by oxidation of organic compounds
fatty acid oxidation
metabolism | acyl- CoA ligase activity
butyrate- CoA ligase activity
catalytic activity | 2 |
| actinin, alpha 1 | ACTN1 | 1 | NP_001093 | cytoskeleton
focal adhesion
pseudopodium | focal adhesion formation
negative regulation of cell motility
regulation of apoptosis | actin binding
calcium ion binding
integrin binding
protein binding
vinculin binding | 2 |
| ARP1 actin- related protein 1 homolog A, centractin alpha | ACTR1A | 1 | NP_005727 | actin filament
cytoplasm
cytoskeleton | not classified | ATP binding
nucleotide binding
protein binding
structural constituent of cytoskeleton | 2 |
| actin- related protein 2 isoform a | ACTR2 | 1 | NP_001005386 | cytoskeleton | not classified | protein binding
structural molecule activity | 2 |
| ARP3 actin- related protein 3 homolog | ACTR3 | 6 | NP_005712 | Arp2/3 protein complex | cell motility | ATP binding
nucleotide binding
protein binding
structural molecule activity | 2 |
| aminoacylase 1 | ACY1 | 15 | NP_000657 | cytoplasm
cytosol | amino acid metabolism
proteolysis | aminoacylase activity
hydrolase activity
metallopeptidase activity
protein dimerization activity
zinc ion binding | 1, 2 |
| aspartoacylase (aminocyclase) 3 | ACY3 | 1 | NP_542389 | not classified | metabolism | aspartoacylase activity
hydrolase activity, acting on ester bonds | 2 |
| brain adenylate cyclase 1 | ADCY1 | 1 | NP_066939 | integral to membrane
membrane | cAMP biosynthesis
intracellular signaling cascade | calcium- and calmodulin- responsive adenylate cyclase activity
calmodulin binding
magnesium ion binding
| 2 |
| class III alcohol dehydrogenase 5 chi subunit | ADH5 | 1 | NP_000662 | not classified | ethanol oxidation | alcohol dehydrogenase activity
electron carrier activity
fatty acid binding
formaldehyde dehydrogenase (glutathione) activity
metal ion binding
S- (hydroxymethyl)glutathione dehydrogenase activity
zinc ion binding | 2 |
| class V alcohol dehydrogenase 6 | ADH6 | 1 | NP_000663 | not classified | ethanol oxidation | alcohol dehydrogenase activity
electron carrier activity
metal ion binding
oxidoreductase activity
zinc ion binding | 2 |
| transcription factor ELYS | AHCTF1 | 1 | NP_056261 | nucleus | development
transcription | DNA binding | 2 |
| S- adenosylhomocysteine hydrolase | AHCY | 10 | NP_000678 | cytoplasm | one- carbon compound metabolism | adenosylhomocysteinase activity
hydrolase activity | 2 |
| AHNAK nucleoprotein isoform 1 | AHNAK | 1 | NP_001611 | nucleus | nervous system
development | protein binding | 2 |
| AHA1, activator of heat shock 90kDa protein ATPase homolog 1 | AHSA1 | 1 | NP_036243 | cytoplasm
endoplasmic reticulum | protein folding
response to stress | ATPase stimulator activity
chaperone activator activity
chaperone binding | 2 |
| alpha- 2- HS- glycoprotein (Fetuin- A) | AHSG | 1 | NP_001613 | extracellular region
extracellular space | acute- phase response
negative regulation of bone mineralization
negative regulation of insulin receptor signaling pathway
pinocytosis
positive regulation of phagocytosis
regulation of inflammatory response
skeletal development | cysteine protease inhibitor activity
kinase inhibitor activity | 2 |
| adenylate kinase 1 | AK1 | 4 | NP_000467 | cytoplasm
cytosol | ATP metabolism
nucleobase, nucleoside, nucleotide
and nucleic acid metabolism | adenylate kinase activity
ATP binding
kinase activity
nucleotide binding
transferase activity | 2 |
| aldo- keto reductase family 1, member A1 | AKR1A1 | 7 | NP_006057 | not classified | aldehyde metabolism
glucose metabolism | alcohol dehydrogenase (NADP+) activity
aldehyde reductase activity
electron carrier activity
oxidoreductase activity
protein binding | 2 |
| aldo- keto reductase family 1, member B1 | AKR1B1 | 3 | NP_001619 | extracellular space | carbohydrate metabolism | aldehyde reductase activity
electron carrier activity
oxidoreductase activity | 1, 2 |
| aldo- keto reductase family 7, member A2 | AKR7A2 | 2 | NP_003680 | not classified | aldehyde metabolism
carbohydrate metabolism | aldehyde reductase activity
electron carrier activity | 2 |
| aldo- keto reductase family 7, member A3 | AKR7A3 | 2 | NP_036199 | cytosol | aldehyde metabolism | aldo- keto reductase activity
electron carrier activity | 2 |
| delta- aminolevulinic acid dehydratase isoform a | ALAD | 1 | NP_001003945 | not classified | heme biosynthesis | lyase activity
metal ion binding
porphobilinogen synthase activity
zinc ion binding | 2 |
| albumin precursor | ALB | 36 | NP_000468 | extracellular region
extracellular space
protein complex | body fluid osmoregulation
cellular response to starvation
hemolysis of host red blood cells
maintenance of mitochondrion localization
negative regulation of apoptosis
negative regulation of non- apoptotic
programmed cell death
transport
water homeostasis | antioxidant activity
carrier activity
copper ion binding
DNA binding
drug binding
fatty acid binding
metal ion binding
oxygen binding
protein binding
pyridoxal phosphate binding
toxin binding
water binding | 1, 2 |
| activated leukocyte cell adhesion molecule | ALCAM | 1 | NP_001618 | integral to plasma membrane
membrane
membrane fraction | antimicrobial humoral response (sensu Vertebrata)
cell adhesion
signal transduction
| receptor binding | 2 |
| aldehyde dehydrogenase 1A1 | ALDH1A1 | 10 | NP_000680 | cytoplasm | aldehyde metabolism
metabolism | aldehyde dehydrogenase (NAD) activity
androgen binding
oxidoreductase activity
Ras GTPase activator activity
retinal dehydrogenase activity | 2 |
| aldehyde dehydrogenase 1 family, member L1 | ALDH1L1 | 9 | NP_036322 | cytoplasm | 10- formyltetrahydrofolate catabolism
biosynthesis
one- carbon compound metabolism
protein biosynthesis | cofactor binding
formyltetrahydrofolate dehydrogenase activity
hydroxymethyl- , formyl- and related transferase activity
methyltransferase activity
oxidoreductase activity | 2 |
| mitochondrial aldehyde dehydrogenase 2 precursor | ALDH2 | 1 | NP_000681 | mitochondrion | alcohol metabolism
carbohydrate metabolism
metabolism | aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
electron carrier activity | 2 |
| aldehyde dehydrogenase 3B1 isoform a | ALDH3B1 | 1 | NP_000685 | not classified | alcohol metabolism
aldehyde metabolism
lipid metabolism
metabolism | 3- chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase [NAD(P)+] activity
oxidoreductase activity | 2 |
| aldehyde dehydrogenase 3B1 isoform b | ALDH3B1 | 1 | NP_001025181 | not classified | alcohol metabolism
aldehyde metabolism
lipid metabolism
metabolism | 3- chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase [NAD(P)+] activity
oxidoreductase activity | 2 |
| aldehyde dehydrogenase 8A1 isoform 1 | ALDH8A1 | 1 | NP_072090 | intracellular | cell surface
extracellular matrix (sensu Metazoa)
membrane | oxidoreductase activity
retinal dehydrogenase activity | 2 |
| aldehyde dehydrogenase 9A1 | ALDH9A1 | 5 | NP_000687 | cytoplasm | aldehyde metabolism
electron transport
hormone metabolism
metabolism
neurotransmitter biosynthesis | 4- trimethylammoniobutyraldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
aminobutyraldehyde dehydrogenase activity
oxidoreductase activity | 2 |
| aldolase A | ALDOA | 7 | NP_908930 | not classified | fructose metabolism
glycolysis
metabolism
striated muscle contraction | fructose- bisphosphate aldolase activity
lyase activity | 2 |
| fructose- bisphosphate aldolase C | ALDOC | 1 | NP_005156 | not classified | fructose metabolism
glycolsis
metabolism | fructose- bisphosphate aldolase activity
lyase activity | 2 |
| anaplastic lymphoma kinase Ki- 1 | ALK | 1 | NP_004295 | integral to plasma membrane
membrane | brain development
nervous system development
protein amino acid N- linked glycosylation
protein amino acid phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway | ATP binding
nucleotide binding
receptor activity
receptor signaling protein tyrosine kinase activity
transferase activity
transmembrane receptor protein tyrosine kinase activity | 2 |
| arachidonate 12- lipoxygenase | ALOX12 | 1 | NP_000688 | cytosol
sarcolemma | anti- apoptosis
arachidonic acid metabolism
cell motility
electron transport
fatty acid oxidation
leukotriene biosynthesis
negative regulation of cell volume
oxygen and reactive oxygen species metabolism
positive regulation of cell adhesion
positive regula | arachidonate 12- lipoxygenase activity
hepoxilin- epoxide hydrolase activity
iron ion binding
lipoxygenase activity
metal ion binding
oxidoreductase activity
potassium channel inhibitor activity | 2 |
| tissue non- specific alkaline phosphatase precursor | ALPL | 3 | NP_000469 | integral to membrane
membrane | metabolism
ossification | alkaline phosphatase activity
GPI anchor binding
hydrolase activity
magnesium ion binding
zinc ion binding | 2 |
| alpha- 1- microglobulin/bikunin precursor | AMBP | 4 | NP_001624 | extracellular region
plasma membrane | anti- inflammatory response
cell adhesion
heme catabolism
negative regulation of immune response
negative regulation of JNK cascade
pregnancy
protein- chromophore linkage
transport | calcium channel inhibitor activity
calcium oxalate binding
heme binding
IgA binding
plasmin inhibitor activity
protein homodimerization activity
transporter activity
trypsin inhibitor activity | 1, 2 |
| amnionless protein precursor | AMN | 1 | NP_112205 | integral to membrane
membrane | development | not classified | 2 |
| angiopoietin- like 2 precursor | ANGPTL2 | 1 | NP_036230 | extracellular space | development | receptor binding | 2 |
| ankyrin repeat and FYVE domain containing 1 isoform 1 | ANKFY1 | 2 | NP_057460 | endosome membrane
membrane | endocytosis | metal ion binding
protein binding
zinc ion binding | 2 |
| ankyrin repeat and FYVE domain containing 1 isoform 2 | ANKFY1 | 2 | NP_065791 | endosome membrane
membrane | endocytosis | metal ion binding
protein binding
zinc ion binding | 2 |
| membrane alanine aminopeptidase precursor | ANPEP | 69 | NP_001141 | ER- Golgi intermediate compartment
integral to plasma membrane | angiogenesis
cell differentiation
proteolysis | aminopeptidase activity
membrane alanyl aminopeptidase activity
metal ion binding
metallopeptidase activity
receptor activity
zinc ion binding | 1, 2 |
| annexin I | ANXA1 | 19 | NP_000691 | cornified envelope
cytoplasm | anti- apoptosis
cell motility
cell surface receptor linked signal transduction
inflammatory response
keratinocyte differentiation
lipid metabolism
peptide cross- linking | calcium ion binding
calcium- dependent phospholipid binding
phospholipase A2 inhibitor activity
phospholipase inhibitor activity
protein binding, bridging
receptor binding
structural molecule activity | 2 |
| annexin A11 | ANXA11 | 31 | NP_665875 | cytoplasm
nuclear envelope
nucleoplasm
nucleus | immune response | calcium ion binding
calcium- dependent phospholipid binding
protein binding | 2 |
| annexin A13 isoform b | ANXA13 | 1 | NP_001003954 | plasma membrane | cell differentiation | calcium ion binding
calcium- dependent phospholipid binding | 2 |
| annexin A2 isoform 2 | ANXA2 | 29 | NP_001002857 | plasma membrane
soluble fraction | skeletal development | calcium ion binding
calcium- dependent phospholipid binding
cytoskeletal protein binding
phospholipase inhibitor activity | 2 |
| annexin A2 isoform 1 | ANXA2 | 20 | NP_001002858 | plasma membrane
soluble fraction | skeletal development | calcium ion binding
calcium- dependent phospholipid binding
cytoskeletal protein binding
phospholipase inhibitor activity | 2 |
| annexin A3 | ANXA3 | 8 | NP_005130 | cytoplasm | signal transduction | calcium ion binding
calcium- dependent phospholipid binding
diphosphoinositol- polyphosphate diphosphatase activity
phospholipase A2 inhibitor activity | 1, 2 |
| annexin IV | ANXA4 | 24 | NP_001144 | cytoplasm | anti- apoptosis
negative regulation of coagulation
signal transduction | calcium ion binding
calcium- dependent phospholipid binding
phospholipase inhibitor activity | 1, 2 |
| annexin 5 | ANXA5 | 24 | NP_001145 | cytoplasm
intracellular | anti- apoptosis
blood coagulation
negative regulation of coagulation
signal transduction | calcium ion binding
calcium- dependent phospholipid binding
phospholipase inhibitor activity
protein binding | 1, 2 |
| annexin VI isoform 1 | ANXA6 | 27 | NP_001146 | not classified | not classified | calcium ion binding
calcium- dependent phospholipid binding
protein binding | 1, 2 |
| annexin VI isoform 2 | ANXA6 | 20 | NP_004024 | not classified | not classified | calcium ion binding
calcium- dependent phospholipid binding
protein binding | 2 |
| annexin VII isoform 2 | ANXA7 | 13 | NP_004025 | not classified | not classified | calcium ion binding
calcium- dependent phospholipid binding
voltage- gated calcium channel activity | 2 |
| annexin VII isoform 1 | ANXA7 | 2 | NP_001147 | not classified | not classified | calcium ion binding
calcium- dependent phospholipid binding
voltage- gated calcium channel activity | 1 |
| aldehyde oxidase 1 | AOX1 | 1 | NP_001150 | not classified | electron transport
inflammatory response
oxygen and reactive oxygen species metabolism | 2 iron, 2 sulfur cluster binding
aldehyde oxidase activity
electron carrier activity
iron ion binding
metal ion binding
molybdenum ion binding
oxidoreductase activity
xanthine dehydrogenase activity | 2 |
| adaptor- related protein complex 1, mu 1 subunit | AP1M1 | 1 | NP_115882 | clathrin vesicle coat
coated pit | intracellular protein transport | protein binding | 2 |
| adaptor- related protein complex 2, mu 1 subunit isoform a | AP2M1 | 1 | NP_004059 | clathrin vesicle coat
coated pit | intracellular protein transport
transport | lipid binding
protein binding
transporter activity | 2 |
| adaptor- related protein complex 4, mu 1 subunit | AP4M1 | 1 | NP_004713 | clathrin vesicle coat
coated pit
coated vesicle membrane
Golgi trans cisterna
membrane coat adaptor complex | intracellular protein transport
transport
vesicle- mediated transport | transporter activity | 2 |
| apoptotic peptidase activating factor 1 isoform b | APAF1 | 1 | NP_001151 | cytosol
intracellular | caspase activation via cytochrome c
nervous system development
regulation of apoptosis | ATP binding
caspase activator activity
nucleotide binding
protein binding | 2 |
| serum amyloid P component precursor | APCS | 5 | NP_001630 | extracellular region
extracellular space | acute- phase response
chaperone- mediated protein complex assembly
protein folding | calcium ion binding
sugar binding
unfolded protein binding | 1, 2 |
| apolipoprotein A- I preproprotein | APOA1 | 6 | NP_000030 | extracellular region
extracellular space | cholesterol metabolism
cholesterol transport
circulation
lipid metabolism
lipid transport
lipoprotein metabolism
steroid metabolism | high- density lipoprotein binding
lipid binding
lipid transporter activity
protein binding | 2 |
| apolipoprotein A- II preproprotein | APOA2 | 1 | NP_001634 | extracellular region | glucose metabolism
lipid transport
negative regulation of lipid catabolism
negative regulation of lipoprotein metabolism
neutrophil activation
positive regulation of interleukin- 8 biosynthesis
regulation of cytokine production
response to glucose stimulus | lipid binding
lipid transporter activity
protein heterodimerization activity
protein homodimerization activity | 2 |
| apolipoprotein A- IV precursor | APOA4 | 2 | NP_000473 | chylomicron
extracellular region | circulation
lipid metabolism
lipid transport
lipoprotein metabolism | lipid binding
lipid transporter activity | 2 |
| apolipoprotein D precursor | APOD | 7 | NP_001638 | extracellular region
extracellular space | lipid metabolism
transport | high- density lipoprotein binding
lipid binding
lipid transporter activity
protein binding | 1, 2 |
| apolipoprotein E precursor | APOE | 6 | NP_000032 | chylomicron
cytoplasm
extracellular region | cholesterol homeostasis
circulation
cytoskeleton organization and biogenesis
induction of apoptosis
intracellular transport
learning and/or memory
lipid transport
lipoprotein metabolism
protein tetramerization
regulation of axon extension
regulation of ne | antioxidant activity
apolipoprotein E receptor binding
beta- amyloid binding
heparin binding
lipid transporter activity
phospholipid binding
tau protein binding | 2 |
| adaptor protein containing pH domain, PTB domain and leucine zipper motif | APPL | 1 | NP_036228 | cytoplasm
endosome membrane
membrane
nucleus
NuRD complex | cell cycle
cell proliferation
signal transduction | protein binding | 2 |
| adenine phosphoribosyltransferase isoform a | APRT | 3 | NP_000476 | cytoplasm | adenine salvage
nucleoside metabolism
purine ribonucleoside salvage | adenine phosphoribosyltransferase activity
AMP binding
transferase activity, transferring glycosyl groups | 1, 2 |
| adenine phosphoribosyltransferase isoform b | APRT | 3 | NP_001025189 | cytoplasm | adenine salvage
nucleoside metabolism
purine ribonucleoside salvage | adenine phosphoribosyltransferase activity
AMP binding
transferase activity, transferring glycosyl groups | 2 |
| aquaporin 1 | AQP1 | 3 | NP_932766 | integral to membrane
integral to plasma membrane
membrane
outer membrane | excretion
transport
water transport | porin activity
transporter activity
water transporter activity | 1, 2 |
| aquaporin 2 | AQP2 | 7 | NP_000477 | apical plasma membrane
integral to membrane
plasma membrane | excretion
transport
water transport | transporter activity
water channel activity | 1, 2 |
| ADP- ribosylation factor 1 | ARF1 | 6 | NP_001649 | intracellular
plasma membrane | ER to Golgi vesicle- mediated transport
transport
rRNA processing
small GTPase mediated signal transduction | GTP binding
GTPase activity
nucleotide binding
protein binding
receptor signaling protein activity | 1 |
| ADP- ribosylation factor interacting protein 1 isoform 2 | ARFIP1 | 1 | NP_055262 | cytosol
Golgi membrane | intracellular protein transport
regulation of protein secretion | not classified | 1 |
| Rho GTPase activating protein 1 | ARHGAP1 | 1 | NP_004299 | intracellular | cytoskeleton organization and biogenesis
Rho protein signal transduction
signal transduction | GTP binding
protein binding
Rho GTPase activator activity
SH3/SH2 adaptor activity | 2 |
| Rho GDP dissociation inhibitor (GDI) alpha | ARHGDIA | 1 | NP_004300 | cytoplasm
cytoskeleton | anti- apoptosis
cell motility
negative regulation of cell adhesion
Rho protein signal transduction | GTPase activator activity
protein binding
Rho GDP- dissociation inhibitor activity | 2 |
| Rho GDP dissociation inhibitor (GDI) beta | ARHGDIB | 1 | NP_001166 | cytoplasm
cytoplasmic membrane- bound vesicle
cytoskeleton | actin cytoskeleton organization and biogenesis
cell motility
development
immune response
negative regulation of cell adhesion
Rho protein signal transduction | GTPase activator activity
Rho GDP- dissociation inhibitor activity | 2 |
| Rho guanine nucleotide exchange factor (GEF) 12 | ARHGEF12 | 1 | NP_056128 | intracellular | regulation of Rho protein signal transduction | GTPase activator activity
protein binding
Rho guanyl- nucleotide exchange factor activity | 2 |
| ADP- ribosylation factor related protein 2 | ARL15 | 1 | NP_061960 | not classified | not classified | GTP binding | 2 |
| ADP- ribosylation factor- like 3 | ARL3 | 2 | NP_004302 | intracellular | G- protein coupled receptor protein signaling pathway
rRNA processing
small GTPase mediated signal transduction | GTP binding
nucleotide binding
signal transducer activity | 1, 2 |
| ADP- ribosylation factor- like 6 | ARL6 | 3 | NP_115522 | cytoplasm
intracellular
membrane | rRNA processing
small GTPase mediated signal transduction | GTP binding
nucleotide binding
protein binding | 2 |
| ADP- ribosylation factor- like 10B | ARL8A | 1 | NP_620150 | cytoplasm
intracellular
membrane
midbody
spindle midzone | chromosome segregation
rRNA processing
small GTPase mediated signal transduction | alpha- tubulin binding
beta- tubulin binding
GTP binding
GTPase activity
nucleotide binding | 2 |
| ADP- ribosylation factor- like 10C | ARL8B | 1 | NP_060654 | cytoplasm
intracellular
membrane
midbody
spindle midzone | chromosome segregation
rRNA processing
small GTPase mediated signal transduction | alpha- tubulin binding
beta- tubulin binding
GDP binding
GTP binding
GTPase activity
nucleotide binding | 2 |
| armadillo repeat containing 3 | ARMC3 | 1 | NP_775104 | not classified | not classified | binding | 2 |
| armadillo repeat containing 9 | ARMC9 | 1 | NP_079415 | not classified | not classified | binding | 2 |
| actin related protein 2/3 complex subunit 1A | ARPC1A | 1 | NP_006400 | not classified | not classified | not classified | 2 |
| actin related protein 2/3 complex subunit 2 | ARPC2 | 5 | NP_005722 | Arp2/3 protein complex
cytoskeleton | cell motility
regulation of actin filament polymerization | structural constituent
of cytoskeleton | 2 |
| actin related protein 2/3 complex subunit 3 | ARPC3 | 2 | NP_005710 | Arp2/3 protein complex | cell motility
regulation of actin filament polymerization | structural constituent
of cytoskeleton | 2 |
| actin related protein 2/3 complex subunit 4 isoform a | ARPC4 | 2 | NP_005709 | Arp2/3 protein complex
cytoskeleton | actin filament polymerization
actin nucleation | actin filament binding
protein binding, bridging
structural constituent of cytoskeleton | 1, 2 |
| actin related protein 2/3 complex subunit 4 isoform b | ARPC4 | 2 | NP_001020130 | Arp2/3 protein complex
cytoskeleton | actin filament polymerization
actin nucleation | actin filament binding
protein binding, bridging
structural constituent of cytoskeleton | 2 |
| actin related protein 2/3 complex subunit 5 | ARPC5 | 1 | NP_005708 | Arp2/3 protein complex
cytoplasm
cytoskeleton | actin cytoskeleton organization and biogenesis
cell motility
regulation of actin filament polymerization | structural constituent
of cytoskeleton | 2 |
| actin related protein 2/3 complex, subunit 5- like | ARPC5L | 1 | NP_112240 | cytoskeleton | regulation of actin filament polymerization | not classified | 2 |
| arrestin domain containing 1 | ARRDC1 | 5 | NP_689498 | not classified | not classified | not classified | 1, 2 |
| arylsulfatase E precursor | ARSE | 1 | NP_000038 | not classified | metabolism
skeletal development | arylsulfatase activity
calcium ion binding
hydrolase activity | 2 |
| arylsulfatase F precursor | ARSF | 12 | NP_004033 | not classified | metabolism | arylsulfatase activity
calcium ion binding
hydrolase activity | 2 |
| N- acylsphingosine amidohydrolase (acid ceramidase) 1 preproprotein isoform a | ASAH1 | 7 | NP_808592 | lysosome | carboxylic acid metabolism
ceramide metabolism
fatty acid metabolism | ceramidase activity
hydrolase activity
transferase activity, transferring acyl groups,
acyl groups converted into alkyl on transfer | 1, 2 |
| N- acylsphingosine amidohydrolase (acid ceramidase) 1 isoform b | ASAH1 | 9 | NP_004306 | lysosome | carboxylic acid metabolism
ceramide metabolism
fatty acid metabolism | ceramidase activity
hydrolase activity
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | 2 |
| argininosuccinate lyase isoform 3 | ASL | 1 | NP_001020117 | cytoplasm | amino acid biosynthesis
arginine biosynthesis
arginine catabolism
urea cycle | argininosuccinate lyase activity
catalytic activity
lyase activity | 2 |
| arsA arsenite transporter, ATP- binding, homolog 1 | ASNA1 | 1 | NP_004308 | cytoplasm
membrane
nucleolus
soluble fraction | anion transport
response to arsenic
transport | arsenite transporter activity
arsenite- transporting ATPase activity
ATP binding
hydrolase activity
nucleotide binding
transporter activity | 2 |
| argininosuccinate synthetase 1 | ASS1 | 20 | NP_000041 | cytoplasm | amino acid biosynthesis
arginine biosynthesis
urea cycle | argininosuccinate synthase activity
ATP binding
ligase activity
nucleotide binding
protein binding | 1, 2 |
| two AAA domain containing protein | ATAD2 | 1 | NP_054828 | not classified | not classified | ATP binding
nucleoside- triphosphatase activity
nucleotide binding | 2 |
| 5- aminoimidazole- 4- carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase | ATIC | 1 | NP_004035 | not classified | nucleobase, nucleoside, nucleotide
and nucleic acid metabolism | hydrolase activity
IMP cyclohydrolase activity
phosphoribosylaminoimidazolecarboxamide formyltransferase activity
transferase activity | 2 |
| Na+/K+ - ATPase beta 1 subunit isoform b | ATP1B1 | 1 | NP_001001787 | integral to membrane
membrane
sodium:potassium- exchanging ATPase complex | ion transport
potassium ion transport
sodium ion transport | potassium ion binding
sodium ion binding
sodium:potassium- exchanging ATPase activity | 2 |
| ATP synthase, H+ transporting,
mitochondrial F1 complex, alpha subunit precursor | ATP5A1 | 3 | NP_001001937 | membrane fraction
mitochondrion
proton- transporting ATP synthase complex (sensu Eukaryota)
proton- transporting ATP synthase complex, catalytic core F(1)
proton- transporting two- sector ATPase complex | ATP synthesis coupled proton transport
ion transport
proton transport | ATP binding
hydrogen- transporting ATP synthase activity, rotational mechanism
hydrogen- transporting ATPase activity, rotational mechanism
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement ofsubstances
meta | 2 |
| ATP synthase, H+ transporting,
mitochondrial F1 complex, beta subunit precursor | ATP5B | 4 | NP_001677 | mitochondrion
proton- transporting ATP synthase complex (sensu Eukaryota)
proton- transporting ATP synthase complex, catalytic core F(1)
proton- transporting ATP synthase, catalytic core (sensu Eukaryota) | ATP synthesis coupled proton transport
generation of precursor metabolites and energy
ion transport
proton transport | ATP binding
hydrogen- exporting ATPase activity, phosphorylative mechanism
hydrogen- transporting ATP synthase activity, rotational mechanism
hydrogen- transporting ATPase activity, rotational mechanism
hydrolase activity
metal ion binding
nucleoside- triphos | 2 |
| ATPase, H+ transporting, lysosomal accessory protein 1 precursor | ATP6AP1 | 1 | NP_001174 | membrane
proton- transportin two- sector ATPase complex
vacuole | ATP synthesis coupled proton transport
ion transport
proton transport | ATP binding
hydrogen- transporting ATP synthase activity, rotational mechanism
hydrogen- transporting ATPase activity, rotational mechanism
hydrolase activity
metal ion binding
nucleotide binding
transporter activity | 2 |
| ATPase, H+ transporting, lysosomal accessory protein 2 | ATP6AP2 | 1 | NP_005756 | integral to membrane
membrane | not classified | receptor activity | 2 |
| ATPase, H+ transporting, lysosomal V0 subunit a isoform 1 | ATP6V0A1 | 1 | NP_005168 | integral to membrane
membrane | ion transport
proton transport | hydrogen ion transporter
activity | 2 |
| ATPase, H+ transporting, lysosomal V0 subunit a4 | ATP6V0A4 | 1 | NP_065683 | hydrogen- translocating V- type ATPase complex
integral to membrane
membrane | ion transport
proton transport
regulation of pH | hydrogen ion transporter
activity | 2 |
| ATPase, H+ transporting, lysosomal, V0 subunit c | ATP6V0C | 1 | NP_001685 | membrane
proton- transporting two- sector ATPase complex
vacuole | ATP synthesis coupled proton transport
ion transport
proton transport | hydrogen- transporting ATP synthase activity, rotational mechanism
hydrogen- transporting ATPase activity, rotation mechanism
hydrolase activity
metal ion binding | 2 |
| ATPase, H+ transporting, lysosomal, V0 subunit d1 | ATP6V0D1 | 1 | NP_004682 | hydrogen- translocating V- type ATPase complex
proton- transporting two- sector ATPase complex | ATP synthesis coupled proton transport
ion transport
proton transport | hydrogen- transporting ATP synthase activity, rotational mechanism
hydrogen- transporting ATPase activity, rotational mechanism
hydrolase activity
metal ion binding | 2 |
| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D2 | ATP6V0D2 | 2 | NP_689778 | |