Department of Health and Human ServicesNational Institutes of HealthNational Heart Lung and Blood Institute
IMCD Proteome Database
NHLBI Division of Intramural ResearchLaboratory of Kidney and Electrolyte Metabolism
BLAST your nucleotide or amino acid sequence against the IMCD Transcriptome Database Download Data

Sort database by:

This database of renal inner medullary collecting duct (IMCD) transcripts is based on Affymetrix array profiling carried out in the NHLBI Laboratory of Kidney and Electrolyte Metabolism (Uawithya et al, Physiol Genomics, 2008). Data are from IMCD cells freshly isolated from the renal medullas of rats. Use the menu bar above to sort the database by the different characteristics.

Signal intensities for IMCD samples and for samples representing non-IMCD elements of the inner medulla (non-IMCD) have been normalized such that the median value for IMCD is 1.0. Values are corrected for cross contamination of samples, i.e. non-IMCD elements on IMCD samples and vice versa.

These experimental data are derived from 3 pairs of Rat 230 2.0 Expression Array from Affymetrix, Inc. Standard error of the mean for all values can be obtained via the Download Data link in this page.

The IMCD Transcriptome Database was created by Panapat Uawithya, Brian Ruttenberg, Guozhong Ma, and Mark A. Knepper. Contact us with questions or comments.

<
Gene NameProbeset IDGene SymbolAcc NOIMCD Signalnon-IMCD SignalIMCD:non-IMCD Ratio
1- acylglycerol- 3- phosphate O- acyltransferase 11392763_atAgpat1NM_2124582.000.952.10
1- acylglycerol- 3- phosphate O- acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (predicted)1374570_atAgpat2_predictedNM_001107821 1.171.011.16
1- acylglycerol- 3- phosphate O- acyltransferase 3 (predicted)1382041_atAgpat3_predictedNM_001106378 1.301.001.31
1- acylglycerol- 3- phosphate O- acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)1368194_atAgpat4NM_1334061.260.167.75
1- acylglycerol- 3- phosphate O- acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) (predicted)1373169_atAgpat5_predictedXM_001074443 0.842.020.41
1- acylglycerol- 3- phosphate O- acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)1372919_atAgpat6NM_001047849 2.675.060.53
2 ' - 5 ' oligoadenylate synthetase 1I1391754_atOas1iNM_0010096800.510.172.94
2, 3- bisphosphoglycerate mutase1388544_atBpgmNM_1993826.783.042.23
2, 4- dienoyl CoA reductase 1, mitochondrial1367777_atDecr1NM_0571974.512.072.18
2', 5'- oligoadenylate synthetase 1, 40/46kDa1371152_a_atOas1NM_1389132.240.882.55
24- dehydrocholesterol reductase1372012_atDhcr24NM_001080148 1.610.652.47
2- 4- dienoyl- Coenzyme A reductase 2, peroxisomal1370818_atDecr2NM_1719961.760.573.09
2'- 5' oligoadenylate synthetase- like 11377497_atOasl1NM_00100968117.52-2.38>100
3- hydroxy- 3- methylglutaryl- Coenzyme A lyase1367767_atHmgclNM_0243861.641.171.40
3- hydroxy- 3- methylglutaryl- Coenzyme A reductase1375852_atHmgcrNM_01313418.930.13>100
3- hydroxy- 3- methylglutaryl- Coenzyme A synthase 11367932_atHmgcs1NM_01726824.850.18>100
3- hydroxybutyrate dehydrogenase, type 11368387_atBdh1NM_0539950.790.117.13
3- hydroxyisobutyrate dehydrogenase1388118_atHibadhNM_02224310.628.571.24
3- hydroxyisobutyryl- Coenzyme A hydrolase1373564_atHibchNM_0010131122.920.853.42
3'- phosphoadenosine 5'- phosphosulfate synthase 1 (predicted)1371850_atPapss1_predictedNM_001106471 6.536.411.02
3- phosphoglycerate dehydrogenase1367811_atPhgdhNM_0316201.135.070.22
3- phosphoinositide dependent protein kinase- 11370052_atPdpk1NM_0310811.331.321.01
4- nitrophenylphosphatase domain and non- neuronal SNAP25- like protein homolog 1 (C. elegans)1390454_atNipsnap1XM_001067526 1.430.602.39
5, 10- methenyltetrahydrofolate synthetase (5- formyltetrahydrofolate cyclo- ligase)1392719_atMthfsNM_0010093493.702.651.40
5'- 3' exoribonuclease 2 (predicted)1391412_atXrn2_predictedNM_001108596 2.231.841.22
5- aminoimidazole- 4- carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase1369962_atAticNM_0310141.752.190.80
5- azacytidine induced gene 21388631_atAzi2NM_0010257050.520.590.88
5- methyltetrahydrofolate- homocysteine methyltransferase reductase1398642_atMtrrNM_0010390031.000.961.04
5'- nucleotidase domain containing 1 (predicted)1392144_atNt5dc1_predictedNM_001106393 1.670.692.41
5'- nucleotidase domain containing 21371849_atNt5dc2NM_0010092713.131.312.38
5'- nucleotidase, cytosolic III (predicted)1373412_atNt5c3_predictedNM_001107862 1.560.951.64
5'- nucleotidase, cytosolic III- like1389131_atNt5c3lNM_001007723 1.811.491.21
6- phosphofructo- 2- kinase/fructose- 2, 6- biphosphatase 31369794_a_atPfkfb3NM_0571356.49-1.05>100
6- phosphogluconolactonase (predicted)1374523_atPgls_predictedNM_001106066 0.690.970.71
6- pyruvoyl- tetrahydropterin synthase1369304_atPtsNM_0172202.290.494.70
7- dehydrocholesterol reductase1368189_atDhcr7NM_0223892.530.554.62
92Aa- protein1371420_atLOC494529NM_001009974 0.982.390.41
a disintegrin and metallopeptidase domain 15 (metargidin)1387135_atAdam15NM_0203082.935.530.53
a disintegrin and metallopeptidase domain 1a1387256_atAdam1aNM_0200780.410.530.76
a disintegrin and metalloprotease domain 101383127_atAdam10XM_001054737 6.845.521.24
a disintegrin and metalloprotease domain 8 (predicted)1390046_atAdam8_predictedNM_001107560 1.422.000.71
a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)1367922_atAdam17NM_0203063.614.340.83
a disintegrin and metalloproteinase domain 9 (meltrin gamma)1375337_atAdam9NM_0010147722.952.281.29
a disintegrin- like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 (predicted)1379022_atAdamts8_predictedNM_001106811 1.390.0916.33
a disintegrin- like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 11368223_atAdamts1NM_0244003.360.477.16
A kinase (PRKA) anchor protein (yotiao) 91383151_atAkap9NM_001037093 2.812.501.12
A kinase (PRKA) anchor protein 11383358_atAkap1NM_0536651.471.041.42
A kinase (PRKA) anchor protein 10 (predicted)1372194_atAkap10_predictedXM_001077273 0.821.000.82
A kinase (PRKA) anchor protein 111368427_atAkap11NM_012773 21.87-1.63>100
A kinase (PRKA) anchor protein 131382268_atAkap13NM_001106271 1.522.270.67
A kinase (PRKA) anchor protein 71389496_atAkap7NM_001001801 1.051.330.79
A kinase (PRKA) anchor protein 81370911_atAkap8XM_001074708 2.292.660.86
A kinase (PRKA) anchor protein 8- like1385713_atAkap8lNM_0010139461.742.220.78
aarF domain containing kinase 1 (predicted)1389599_atAdck1_predictedNM_001108985 0.411.070.38
aarF domain containing kinase 41389043_atAdck4NM_001012065 0.590.960.61
aarF domain containing kinase 51375506_atAdck5XM_001075206 5.440.658.32
Ab1- 2191385397_atLOC499991NM_001044265 1.011.160.87
Abelson helper integration site 11394895_atAhi1NM_0010022770.590.292.03
abhydrolase domain containing 11374475_atAbhd1NM_0010085201.300.1310.24
abhydrolase domain containing 14b1388988_atAbhd14bNM_0010076649.542.493.84
abhydrolase domain containing 2 (predicted)1390455_atAbhd2_predictedNM_001106275 0.780.601.31
abhydrolase domain containing 3 (predicted)1382137_atAbhd3_predictedNM_001106162 1.180.186.54
abhydrolase domain containing 4 (predicted)1399019_atAbhd4_predictedNM_001108866 3.712.951.26
abhydrolase domain containing 51379854_atAbhd5NM_2125240.960.146.71
abhydrolase domain containing 61390155_atAbhd6NM_0010076801.351.410.96
abhydrolase domain containing 8 (predicted)1393197_atAbhd8_predictedNM_001107301 0.600.571.05
abl- interactor 11372360_atAbi1NM_0243975.004.341.15
abl- interactor 21387909_atAbi2NM_173143 2.882.651.08
ABO blood group (transferase A, alpha 1- 3- N- acetylgalactosaminyltransferase; transferase B, alpha 1- 3- galactosyltransferase)1393031_atAboNM_0230940.481.190.40
Ac12541372249_atLOC362901NM_00100887713.166.871.91
acetoacetyl- CoA synthetase1368126_atAacsNM_0231042.690.505.42
acetyl- coenzyme A acetyltransferase 11367763_atAcat1NM_0170756.582.093.15
acetyl- Coenzyme A acetyltransferase 21372462_atAcat2NM_0010069951.700.632.69
acetyl- Coenzyme A acyltransferase 1 1387783_a_atAcaa1 NM_001040019 0.560.880.63
acetyl- Coenzyme A acyltransferase 2 (mitochondrial 3- oxoacyl- Coenzyme A thiolase)1386880_atAcaa2NM_1304336.012.252.67
acetyl- Coenzyme A carboxylase alpha1370893_atAcacaNM_0221930.991.150.86
acetyl- Coenzyme A dehydrogenase, long- chain1367735_atAcadlNM_0128193.882.331.67
acetyl- Coenzyme A dehydrogenase, medium chain1367702_atAcadmNM_01698618.003.654.93
acetyl- Coenzyme A dehydrogenase, short chain1367828_atAcadsNM_0225121.540.522.97
acetylserotonin O- methyltransferase- like (predicted)1372228_atAsmtl_predictedNM_001105915 2.111.491.41
acid phosphatase 1, soluble1398938_atAcp1NM_0212623.502.441.43
acid phosphatase 2, lysosomal1367906_atAcp2NM_0169881.521.940.78
acid phosphatase 5, tartrate resistant1367942_atAcp5NM_0191441.980.395.06
acid phosphatase 6, lysophosphatidic1373732_atAcp6NM_0010316451.610.921.76
acid phosphatase- like 21389229_atAcpl2NM_001007710 3.980.419.66
acidic (leucine- rich) nuclear phosphoprotein 32 family, member A1369063_atAnp32aNM_012903 2.856.570.43
acidic (leucine- rich) nuclear phosphoprotein 32 family, member E1371873_atAnp32eNM_0010132005.294.331.22
acidic nuclear phosphoprotein 32 family, member B1386915_atAnp32bNM_1319118.576.391.34
acidic ribosomal phosphoprotein P01367560_atArbpNM_02240227.7638.270.73
acireductone dioxygenase 11389363_atAdi1NM_1990973.511.821.93
ACN9 homolog (S. cerevisiae)1372847_atAcn9NM_001047914 0.520.501.05
aconitase 11386916_atAco1NM_0173212.811.571.79
aconitase 2, mitochondrial1367589_atAco2NM_02439810.713.912.74
acrosin binding protein1398552_a_atAcrbpNM_0010250497.04-1.01>100
actin related protein 2/3 complex, subunit 1A1398779_atArpc1aNM_0311468.161.674.88
actin related protein 2/3 complex, subunit 1B1386925_atArpc1bNM_01928915.268.731.75
actin related protein 2/3 complex, subunit 2 (predicted)1371511_atArpc2_predictedNM_001106919 24.3317.321.41
actin related protein 2/3 complex, subunit 3 (predicted)1371977_atArpc3_predictedNM_001105933 20.7912.331.69
actin related protein 2/3 complex, subunit 4 (predicted)1372577_atArpc4_predictedNM_001106615 2.103.780.56
actin related protein 2/3 complex, subunit 51390022_atArpc5NM_0010257179.099.750.93
actin related protein 2/3 complex, subunit 5- like 1375641_atArpc5l NM_001037767 7.422.572.89
actin, betaAFFX_Rat_beta- actin_3_atActbNM_03114454.2540.891.33
actin, gamma, cytoplasmic 1 1371327_a_atActg1 XM_001058533 60.7253.201.14
actin, gamma, cytoplasmic 1 1384581_atActg1 XM_001058533 0.890.432.05
actinin alpha 41369942_atActn4NM_03167514.908.071.85
actinin, alpha 11389189_atActn1NM_0310054.532.162.10
actin- like 6A1373849_atActl6aNM_0010390332.731.641.67
activated leukocyte cell adhesion molecule1370043_atAlcamNM_0317539.753.332.93
activating signal cointegrator 1 complex subunit 11375907_atAscc1NM_0010076320.740.721.04
activating signal cointegrator 1 complex subunit 3 (predicted)1377755_atAscc3_predictedNM_001107640 1.620.802.02
activating signal cointegrator 1 complex subunit 3- like 11388354_atAscc3l1---*2.843.310.86
activating transcription factor 11389623_atAtf1XM_001064437 3.544.570.78
activating transcription factor 21369472_a_atAtf2NM_0310180.450.241.92
activating transcription factor 31369268_atAtf3NM_012912 48.1728.001.72
activating transcription factor 41367624_atAtf4NM_02440323.4112.611.86
activating transcription factor 51372601_atAtf5NM_1723361.210.821.48
activating transcription factor 7 interacting protein (predicted)1395687_atAtf7ip_predictedNM_001107893 0.460.123.91
activator of basal transcription 11388601_atAbt1NM_001025674 0.870.851.03
active BCR- related gene (predicted)1373215_atAbr_predictedNM_001105814 0.401.490.27
activin receptor IIA1381220_atAcvr2aNM_0315710.951.040.91
Activity and neurotransmitter- induced early gene 1 (ania- 1) mRNA, 3'UTR1385757_at---*---*0.470.860.55
Activity and neurotransmitter- induced early gene 11 (ania- 11) mRNA, 3' UTR1376125_at---*---*4.050.874.66
activity and neurotransmitter- induced early gene protein 4 (ania- 4)1387276_atAnia4---*0.661.910.34
activity regulated cytoskeletal- associated protein1387068_atArcNM_0193611.221.510.81
activity- dependent neuroprotective protein1389088_atAdnpNM_0226813.833.950.97
acyl- CoA synthetase long- chain family member 11370939_atAcsl1NM_0128202.592.830.92
acyl- CoA synthetase long- chain family member 31368177_atAcsl3NM_0571071.583.340.47
acyl- CoA synthetase long- chain family member 41387101_atAcsl4NM_0536235.852.302.54
acyl- CoA synthetase long- chain family member 51386926_atAcsl5NM_0536076.159.680.64
acyl- CoA synthetase short- chain family member 1 (predicted)1372162_atAcss1_predictedNM_001106524 2.752.041.35
acyl- CoA synthetase short- chain family member 2 (predicted)1375944_atAcss2_predictedNM_001107793 3.140.833.80
acyl- CoA thioesterase 71370313_atAcot7NM_0132141.350.403.34
acyl- CoA thioesterase 81368206_atAcot8NM_1307561.210.681.79
acyl- Coenzyme A binding domain containing 31372552_atAcbd3NM_1828431.481.580.94
acyl- Coenzyme A binding domain containing 41373253_atAcbd4NM_0010120130.570.620.92
acyl- Coenzyme A binding domain containing 61374555_atAcbd6NM_0010119060.720.800.90
acyl- Coenzyme A dehydrogenase family, member 11 (predicted)1390789_atAcad11_predictedNM_001108181 1.280.304.33
acyl- Coenzyme A dehydrogenase family, member 91373389_atAcad9XM_001059349 1.791.231.46
acyl- Coenzyme A dehydrogenase, short/branched chain1369526_atAcadsbNM_0130841.270.0254.89
acyl- Coenzyme A dehydrogenase, very long chain1367897_atAcadvlNM_0128912.231.461.53
acyl- Coenzyme A oxidase 1, palmitoyl1367680_atAcox1NM_0173404.993.221.55
acylpeptide hydrolase1398815_atApehNM_0125002.942.521.17
acylphosphatase 1, erythrocyte (common) type (predicted)1373448_atAcyp1_predictedNM_001106746 1.450.622.35
adaptor protein complex AP- 1, beta 1 subunit1367872_atAp1b1NM_0172773.342.111.58
adaptor protein complex AP- 1, sigma 1 (predicted)1377769_atAp1s1_predictedNM_001108331 5.291.214.36
adaptor protein complex AP- 2, alpha 2 subunit1369982_atAp2a2NM_0310086.193.481.78
adaptor- related protein complex 1, gamma 1 subunit1373816_atAp1g1XM_001072391 2.481.351.84
adaptor- related protein complex 2, beta 1 subunit1367704_atAp2b1NM_0805837.114.401.62
adaptor- related protein complex 2, mu 1 subunit1398765_atAp2m1NM_05383714.7014.541.01
adaptor- related protein complex 2, sigma 1 subunit1386877_atAp2s1NM_0229522.672.820.95
adaptor- related protein complex 3, beta 1 subunit (predicted)1373888_atAp3b1_predictedNM_001107646 2.442.121.15
adaptor- related protein complex 3, delta 1 subunit1367549_a_atAp3d1XM_001076208 15.459.811.57
adaptor- related protein complex 3, mu 1 subunit1368062_atAp3m1NM_1335932.821.222.32
adaptor- related protein complex 3, mu 2 subunit1368246_atAp3m2NM_1333050.660.242.74
adaptor- related protein complex 3, sigma 1 subunit (predicted)1373024_atAp3s1_predictedNM_001106933 3.221.921.68
adaptor- related protein complex AP- 1, mu subunit 11372045_atAp1m1NM_001044239 1.011.640.61
adaptor- related protein complex AP- 4, beta 1 (predicted)1376874_a_atAp4b1_predictedNM_001107709 0.961.230.78
adducin 1 (alpha)1388487_atAdd1NM_0169907.545.481.38
adducin 3 (gamma)1370260_atAdd3NM_0315520.520.770.68
adenine phosphoribosyl transferase (predicted)1371244_atAprt_predictedNM_0010130612.939.460.31
adenomatosis polyposis coli1387837_atApcNM_0124990.570.321.79
adenomatosis polyposis coli 2 (predicted)1397579_x_atApc2_predictedNM_001106769 0.700.302.33