1. Protein levels in vaccinated and unvaccinated SARS-CoV-2 patients in the acute and recovery phases of infection

A) Beeswarm plot (with medians) for unvaccinated patients (n=66) & vaccinated patients(n=24) in the acute phase of infection and HC (n=20)

The p-values are adjusted for age, gender, race, and days from symptoms onset based on rank-based inverse normal transformation of the biomarker value. FDR-adjusted p value (adjusted over 7288 proteins) is shown for each pairwise comparison.

B) Linear plot (with medians) for unvaccinated patients (n=22) & vaccinated patients (n=10) in the acute and recovery phases of infection and healthy controls (n=20)

The p-values are adjusted for age, gender, and race on rank-based inverse normal transformation of the biomarker value. FDR-adjusted p value (adjusted over 7288 proteins) is shown for each pairwise comparison.

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2. Protein levels in four clusters of SARS-CoV-2 patients identified via hierarchical clustering and healthy controls in the acute and recovery phases of infection

A) Beeswarm plot (with medians) for four clusters of SARS-CoV-2 patients (n=90) in the acute phase of infection and healthy controls (n=20)

The p-values are adjusted for age, gender, and race on rank-based inverse normal transformations of the biomarker value, with FDR-adjusted p value (adjusted over 7288 proteins)

B) Linear plot (with medians) for four clusters of SARS-CoV-2 patients (n=32) in the acute and recovery phases of infection and healthy controls (n=20)